Using rpath has huge drawbacks, including security implications. With NoMachine's nxserver and nxclient there is no need to do that, as both subsystems set the paths before running the other components. This makes it possible to run different versions of the executables and libraries based on the administrator's settings.

 See also the following related article explaining how NX is designed to work side by side with X11 libraries installed on the system: 

https://www.nomachine.com/AR01C00132